1. What is PSA Adjustment?

PSA (Prostate-Specific Antigen) adjustment involves modifying PSA values based on various factors to provide a more accurate assessment of prostate health and cancer risk.

2. How Does the Calculator Work?

The calculator uses established PSA adjustment formulas:

Where:

• PSA — Prostate-Specific Antigen level (ng/mL)
• Age — Patient's age in years
• Race — Patient's racial background

Explanation: The adjustment accounts for normal variations in PSA levels based on demographic factors.

3. Importance of PSA Adjustment

Details: Proper PSA adjustment helps in more accurate prostate cancer screening, reducing false positives and unnecessary biopsies while maintaining detection sensitivity.

4. Using the Calculator

Tips: Enter PSA level in ng/mL, age in years, and select race. All values must be valid (PSA > 0, age between 40-120).

5. Frequently Asked Questions (FAQ)

Q1: Why adjust PSA levels?
A: PSA levels naturally vary with age and race. Adjustment provides more accurate cancer risk assessment.

Q2: What are normal PSA values?
A: Normal PSA values typically range from 0-4 ng/mL, but vary by age and race.

Q3: When should PSA be measured?
A: PSA testing is generally recommended for men over 50, or earlier for those with risk factors.

Q4: Are there limitations to PSA adjustment?
A: Adjustment formulas may not account for all individual variations and should be used alongside clinical assessment.

Q5: Should adjusted PSA replace original values?
A: Adjusted values provide context but original PSA levels should still be considered in clinical decision-making.